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Friday, December 25, 2009

Lessons from 60 years of pharmaceutical innovation

In an article titled "Lessons from 60 years of pharmaceutical innovation" by Bernard Munos in the Nature Reviews Drug Discovery 8, 959-968 (December 2009) we read:

"... by analysing data on the companies that introduced the 1,200 new drugs that have been approved by the FDA since 1950. This analysis shows that the new-drug output from pharmaceutical companies in this period has essentially been constant, and remains so despite the attempts to increase it. ... the new-drug output is not depressed, but may simply reflect the limitations of the current R&D model."

See also the editorial in the same issue, titled "Escaping the pincer"

I wonder about the results of analogous studies in other research areas; physical science, software, etc.

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I am a senior software developer working for General Motors Corporation.. I am interested in intelligent computing and scientific computing. I am passionate about computers as enablers for human imagination. The contents of this site are not in any way, shape, or form endorsed, approved, or otherwise authorized by HP, its subsidiaries, or its officers and shareholders.

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