In this joint study by New York University and MIT Lincoln Laboratory, and Northeastern University, defects are intentionally injected into programs. Next, commercial tools are used to discover them. The result has been that the commercial tools could only detect 1 to 2 % of the injected bugs. Please see below:
http://engineering.nyu.edu/press-releases/2016/07/06/building-better-computer-bug-finder
For details, access the paper here:
http://www.ieee-security.org/TC/SP2016/papers/0824a110.pdf
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